Found 27 matching trials
Efficacy, Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity Study of Ravulizumab in Chinese Adults With Neuromyelitis Optica Spectrum Disorder (NMOSD) PHASE3 The primary objective of this study is to confirm the efficacy, safety, pha...
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A Study of a Single Subcutaneous Dose of ALXN1210 in Healthy Adult Participants PHASE1 This study evaluated the safety and tolerability of a single dose of ALXN12...
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Open-label, Multiple Ascending Dose Study of Ravulizumab (ALXN1210) in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) PHASE2 The primary purpose of this study is to evaluate the safety, tolerability, ...
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Efficacy, Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Ravulizumab in Chinese Adults Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) PHASE3 The primary objective of this study is to evaluate the efficacy of ravulizu...
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Safety and Efficacy of OMS906 in Paroxysmal Nocturnal Hemoglobinuria Patients With a Sub-optimal Response to Ravulizumab PHASE2 The purpose of this study is to assess the safety, tolerability, pharmacoki...
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Omeros Investigational Site
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ALXN1210 (Ravulizumab) Versus Eculizumab in Complement Inhibitor Treatment-Naïve Adult Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) PHASE3 The primary purpose of this study was to assess the noninferiority of ravul...
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A Study of Multiple Doses of ALXN1210 in Healthy Adult Participants PHASE1 This study evaluated the safety and tolerability of multiple doses of ALXN1...
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A Study of a Single Dose of ALXN1210 in Healthy Participants PHASE1 This study evaluated the safety, tolerability, pharmacokinetics (PK) and ph...
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An Efficacy and Safety Study of Ravulizumab in Adult Participants With NMOSD PHASE3 The primary purpose of this study is to evaluate the efficacy and safety of...
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Evaluation of PK, PD, Efficacy, Safety, and Immunogenicity of IV Ravulizumab in Pediatric Participants With Generalized Myasthenia Gravis PHASE3 The primary purpose of this study is to characterize the pharmacokinetics a...
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